Глутатион и кетогенная диета

30 января 2024


! Agarwal, R., & Shukla, G. S. (1999). Potential Role of Cerebral Glutathione in the Maintenance of Blood-Brain Barrier Integrity in Rat. Neurochemical Research, 24(12), 1507–1514. https://doi.org/10.1023/A:1021191729865

Amatore, D., Celestino, I., Brundu, S., Galluzzi, L., Coluccio, P., Checconi, P., Magnani, M., Palamara, A. T., Fraternale, A., & Nencioni, L. (2019). Glutathione increase by the n-butanoyl glutathione derivative (GSH-C4) inhibits viral replication and induces a predominant Th1 immune profile in old mice infected with influenza virus. FASEB BioAdvances, 1(5), 296–305. https://doi.org/10.1096/fba.2018-00066

Becker, K., Pons-Kühnemann, J., Fechner, A., Funk, M., Gromer, S., Gross, H.-J., Grünert, A., & Schirmer, R. H. (2005). Effects of antioxidants on glutathione levels and clinical recovery from the malnutrition syndrome kwashiorkor – a pilot study. Redox Report, 10(4), 215–226. https://doi.org/10.1179/135100005X70161

Brennan, B. P., Jensen, J. E., Perriello, C., Pope Jr., H. G., Jenike, M. A., Hudson, J. I., Rauch, S. L., & Kaufman, M. J. (2016). Lower Posterior Cingulate Cortex Glutathione Levels in Obsessive-Compulsive Disorder. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 1(2), 116–124. https://doi.org/10.1016/j.bpsc.2015.12.003

Cellular bioenergetics, caspase activity and glutathione in murine lungs infected with influenza A virus—ScienceDirect. (n.d.). Retrieved February 26, 2022, from https://www.sciencedirect.com/science/article/pii/S0042682213004546

Dringen, R. (2000). Metabolism and functions of glutathione in brain. Progress in Neurobiology, 62(6), 649–671. https://doi.org/10.1016/s0301-0082(99)00060-x

Freed, R. D., Hollenhorst, C. N., Weiduschat, N., Mao, X., Kang, G., Shungu, D. C., & Gabbay, V. (2017). A pilot study of cortical glutathione in youth with depression. Psychiatry Research: Neuroimaging, 270, 54–60. https://doi.org/10.1016/j.pscychresns.2017.10.001

Freeman, L. R., & Keller, J. N. (2012). Oxidative stress and cerebral endothelial cells: Regulation of the blood–brain-barrier and antioxidant based interventions. Biochimica et Biophysica Acta (BBA) – Molecular Basis of Disease, 1822(5), 822–829. https://doi.org/10.1016/j.bbadis.2011.12.009

Fung, L., & Hardan, A. (2019). Oxidative Stress in Psychiatric Disorders. In R. E. Frye & M. Berk (Eds.), The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine (pp. 53–72). Springer. https://doi.org/10.1007/978-981-10-5311-5_4

Glutathione: What It Is, Why You Need It, How You Can Increase It. (n.d.). The Amino Company. Retrieved February 25, 2022, from https://aminoco.com/blogs/nutrition/glutathione

Gomes, T., Oliveira, S., Ataíde, T., & Trindade-Filho, E. (2010). The role of the ketogenic diet on oxidative stress present in experimental epilepsy. Journal of Epilepsy and Clinical Neurophysiology, 17, 54–64. https://doi.org/10.1590/S1676-26492011000200005

Greco, T., Glenn, T. C., Hovda, D. A., & Prins, M. L. (2016). Ketogenic diet decreases oxidative stress and improves mitochondrial respiratory complex activity. Journal of Cerebral Blood Flow & Metabolism, 36(9), 1603–1613. https://doi.org/10.1177/0271678X15610584

Jarrett, S. G., Milder, J. B., Liang, L.-P., & Patel, M. (2008). The ketogenic diet increases mitochondrial glutathione levels. Journal of Neurochemistry, 106(3), 1044–1051. https://doi.org/10.1111/j.1471-4159.2008.05460.x

Kephart, W. C., Mumford, P. W., Mao, X., Romero, M. A., Hyatt, H. W., Zhang, Y., Mobley, C. B., Quindry, J. C., Young, K. C., Beck, D. T., Martin, J. S., McCullough, D. J., D’Agostino, D. P., Lowery, R. P., Wilson, J. M., Kavazis, A. N., & Roberts, M. D. (2017). The 1-Week and 8-Month Effects of a Ketogenic Diet or Ketone Salt Supplementation on Multi-Organ Markers of Oxidative Stress and Mitochondrial Function in Rats. Nutrients, 9(9), E1019. https://doi.org/10.3390/nu9091019

Kim, Y., Park, J., & Choi, Y. K. (2019). The Role of Astrocytes in the Central Nervous System Focused on BK Channel and Heme Oxygenase Metabolites: A Review. Antioxidants, 8(5). https://doi.org/10.3390/antiox8050121

Liu, C., Zhang, N., Zhang, R., Jin, L., Petridis, A. K., Loers, G., Zheng, X., Wang, Z., & Siebert, H.-C. (2020). Cuprizone-Induced Demyelination in Mouse Hippocampus Is Alleviated by Ketogenic Diet. Journal of Agricultural and Food Chemistry, 68(40), 11215–11228. https://doi.org/10.1021/acs.jafc.0c04604

McCarty, M. F., O’Keefe, J. H., & DiNicolantonio, J. J. (2018). Dietary Glycine Is Rate-Limiting for Glutathione Synthesis and May Have Broad Potential for Health Protection. Ochsner Journal, 18(1), 81–87.

Milder, J., & Patel, M. (2012). Modulation of oxidative stress and mitochondrial function by the ketogenic diet. Epilepsy Research, 100(3), 295–303. https://doi.org/10.1016/j.eplepsyres.2011.09.021

Morris, A. a. M. (2005). Cerebral ketone body metabolism. Journal of Inherited Metabolic Disease, 28(2), 109–121. https://doi.org/10.1007/s10545-005-5518-0

Muri, J., Thut, H., Heer, S., Krueger, C. C., Bornkamm, G. W., Bachmann, M. F., & Kopf, M. (2019). The thioredoxin-1 and glutathione/glutaredoxin-1 systems redundantly fuel murine B-cell development and responses. European Journal of Immunology, 49(5), 709–723. https://doi.org/10.1002/eji.201848044

Napolitano, A., Longo, D., Lucignani, M., Pasquini, L., Rossi-Espagnet, M. C., Lucignani, G., Maiorana, A., Elia, D., De Liso, P., Dionisi-Vici, C., & Cusmai, R. (2020). The Ketogenic Diet Increases In Vivo Glutathione Levels in Patients with Epilepsy. Metabolites, 10(12), E504. https://doi.org/10.3390/metabo10120504

Parry, H. A., Kephart, W. C., Mumford, P. W., Romero, M. A., Mobley, C. B., Zhang, Y., Roberts, M. D., & Kavazis, A. N. (2018). Ketogenic diet increases mitochondria volume in the liver and skeletal muscle without altering oxidative stress markers in rats. Heliyon, 4(11), e00975. https://doi.org/10.1016/j.heliyon.2018.e00975

Perry, T. L., Godin, D. V., & Hansen, S. (1982). Parkinson’s disease: A disorder due to nigral glutathione deficiency? Neuroscience Letters, 33(3), 305–310. https://doi.org/10.1016/0304-3940(82)90390-1

Pocernich, C. B., & Butterfield, D. A. (2012). Elevation of glutathione as a therapeutic strategy in Alzheimer’s disease. Biochimica et Biophysica Acta (BBA) – Molecular Basis of Disease, 1822(5), 625–630. https://doi.org/10.1016/j.bbadis.2011.10.003

Rossetti, A. C., Paladini, M. S., Riva, M. A., & Molteni, R. (2020). Oxidation-reduction mechanisms in psychiatric disorders: A novel target for pharmacological intervention. Pharmacology & Therapeutics, 210, 107520. https://doi.org/10.1016/j.pharmthera.2020.107520

Si, J., Wang, Y., Xu, J., & Wang, J. (2020). Antiepileptic effects of exogenous β‑hydroxybutyrate on kainic acid‑induced epilepsy. Experimental and Therapeutic Medicine, 20(6), 1–1. https://doi.org/10.3892/etm.2020.9307

Sido, B., Hack, V., Hochlehnert, A., Lipps, H., Herfarth, C., & Dröge, W. (1998). Impairment of intestinal glutathione synthesis in patients with inflammatory bowel disease. Gut, 42(4), 485–492. https://doi.org/10.1136/gut.42.4.485

Simeone, T. A., Simeone, K. A., Stafstrom, C. E., & Rho, J. M. (2018). Do Ketone Bodies Mediate the Anti-Seizure Effects of the Ketogenic Diet? Neuropharmacology, 133, 233. https://doi.org/10.1016/j.neuropharm.2018.01.011

The Great Plains Laboratory, LLC. (2015, July 17). What Happens When Glutathione is Deficient by Dr  Tim Guilford. https://www.youtube.com/watch?v=OAiy03DcRsM

Veech, R. L., Chance, B., Kashiwaya, Y., Lardy, H. A., & Cahill Jr, G. F. (2001). Ketone Bodies, Potential Therapeutic Uses. IUBMB Life, 51(4), 241–247. https://doi.org/10.1080/152165401753311780

Winterbourn, C. (2018). Regulation of intracellular glutathione. Redox Biology, 22, 101086. https://doi.org/10.1016/j.redox.2018.101086

Zalachoras, I., Hollis, F., Ramos-Fernández, E., Trovo, L., Sonnay, S., Geiser, E., Preitner, N., Steiner, P., Sandi, C., & Morató, L. (2020). Therapeutic potential of glutathione-enhancers in stress-related psychopathologies. Neuroscience & Biobehavioral Reviews, 114, 134–155. https://doi.org/10.1016/j.neubiorev.2020.03.015

Zeevalk, G., Bernard, L., & Guilford, F. (2010). Liposomal-Glutathione Provides Maintenance of Intracellular Glutathione and Neuroprotection in Mesencephalic Neuronal Cells. Neurochemical Research, 35, 1575–1587. https://doi.org/10.1007/s11064-010-0217-0

Ziegler, D. R., Ribeiro, L. C., Hagenn, M., Siqueira, I. R., Araújo, E., Torres, I. L. S., Gottfried, C., Netto, C. A., & Gonçalves, C.-A. (2003). Ketogenic diet increases glutathione peroxidase activity in rat hippocampus. Neurochemical Research, 28(12), 1793–1797. https://doi.org/10.1023/a:1026107405399